Preparation of N, N-dichloropolystyrene sulfonamide nanofiber as a regenerable self-decontaminating material for protection against chemical warfare agents

preparation of n, n-dichloropolystyrene sulfonamide nanofiber as a regenerable self-decontaminating material for protection against chemical warfare agents

n,n-dichloropolystyrene sulfonamide as a decontaminant was synthesized in 5 steps from styrene monomer. styrene was first polymerized. then, sulfonation reaction was performed by h2so4 (c) followed by chlorination with pocl3 obtain chlorosulfonated polystyrene. amidification reaction was then applied to get sulfonamide resin. sulfonamide resin was treated with sodium hypochloride to obtain n,n-...

Transcriptional inducers of acetylcholinesterase expression as novel antidotes for protection against chemical warfare agents

The biological effects of organophosphorous chemical warfare agents (CWAs) are exerted by inhibition of acetylcholinesterase (AChE), which blocks the hydrolysis of acetylcholine leading to hypercholinergy, seizures, status epilepticus, respiratory/ cardiovascular failure and death. Current investigations show that bio-scavenger therapy, using purified fetal bovine AChE and the more recently tes...

Green Chemical Synthesis and Biological Evaluation of Novel N-substituted Rhodanine Derivatives as Potential Antifungal Agents

Background and purpose: In medicinal chemistry, molecules containing rhodanine(2-thiazolidine-4-one) ring as a magic multifunctional privileged structural and functional scaffold show a broad range of potent pharmacological properties containing anti-microbial, antiviral, anti-diabetic, and anti-convulsant effects. Evidence suggests that the activity of the rhodanine derivative correlates with ...

Chemical Warfare Agents

Computational study of electronic, spectroscopic, and chemical properties of (CdO)n (n=1-7) nanoclusters as a transparent conducting oxide

An ab initio study has been performed for the electronic, spectroscopic, and chemical properties of the most stable configuration of the (CdO)n nanoclusters by employing B3LYP-DFT/LanL2DZ method. Different isomers were optimized to obtain structural stability and numerous chemical parameters such as dipole moment, ionization potential, etc. We report here the vibrational frequencies of the most...